American Journal of Life Sciences

Volume 11, Issue 2, April 2023

  • Review on Classification and Nomenclature of Viruses

    Solomon Bimrew, Merkuz Abera

    Issue: Volume 11, Issue 2, April 2023
    Pages: 11-23
    Received: Mar. 31, 2023
    Accepted: Apr. 23, 2023
    Published: May 10, 2023
    Abstract: Viruses are subcellular, infectious, non-living creatures that can only replicate and metabolize inside the cells of living hosts. Virus taxonomy is the classification of viruses into categories called taxa. The classification and nomenclature recently gained importance due to the exponentially increasing number of new viruses discovered. Hence the... Show More
  • Improvement of Phenolic Compounds and Antihyperlipidemic Activity of Hibiscus sabdariffa L. Calyxes Powder Using CDS Processing

    Linda Stella Mbassi, Elie Baudelaire Djantou, Richard Marcel Nguimbou, Amadou Dicko, Nicolas Yanou Njintang

    Issue: Volume 11, Issue 2, April 2023
    Pages: 24-35
    Received: Mar. 10, 2022
    Accepted: Aug. 11, 2022
    Published: Jun. 09, 2023
    Abstract: The aim of this study was to evaluate the effect of controlled differential sieving processing (CDSp) on the content of phenolic compounds and antihyperlipidemic activity of H. sabdariffa calyxes powder. For this, four granulometric classes (<180 μm, 180-212 μm, 212-315 μm, ≥315 μm) were analyzed. Unsieved powder and lyophilized ethanolic extract were used for comparison. First, we identified and quantified the phenolic compounds present in the samples by chromatography in liquid phase coupled to a UV detector and mass spectrometry (LC-MS). Second, we evaluated the antihyperlipidemic activity of the different fractions in adult male rats at a dose of 250 mg/kg and compared them with those of unsieved powder and the ethanolic extract. LC-MS analysis identified seven compounds (quercetin, rutin, catechin, ferrulic acid, p-coumaric acid, protocatechic acid and cafeic acid) in the different sample of H. sabdariffa calyxes powder. The granulometric class 212-315 μm showed the best concentration, higher than ... Show More