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Serologic Hepatitis B Immunity in Vaccinated Health Care Workers

Received: 23 January 2015     Accepted: 6 February 2015     Published: 12 May 2015
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Abstract

The risk of acquiring hepatitis B infection through exposure for blood or its product is highest among health care workers. The most important approach for the prevention of occupational HBV infection is the use of hepatitis B vaccine among HCWs at risk. The present study was undertaken to assess the immune status of HBV vaccinated health care workers. A total of 268 HCWs of Adichunchanagiri Hospital and Research Centre attached to AIMS, B.G.Nagara were enrolled for the study .The study group includes doctors (113), medical & nursing students (61), nurses (59), technicians (15), group D workers (12) and others (8). The serum samples of the participants were tested for Anti-HBsAb levels using ELISA kit (Diasorin, Italy). Anti HBsAb titre of ≥ 10mIU/ml was considered as immune and < 10 mIU /ml as non-immune. The mean age of the study group was 29.49 years. Of the 268 participants 54.85% were female and 45.14% male. 23.5% had history of complete vaccination and 76.49% had incomplete vaccination (1/2 doses). 72.01% were immune and 27.98% non immune. There is a need for stringent and clear policies for HBV screening, vaccination and post vaccination assessment.

Published in American Journal of Life Sciences (Volume 3, Issue 3)
DOI 10.11648/j.ajls.20150303.16
Page(s) 162-166
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Health Care Workers, HBV Vaccine, Anti HBsAb

References
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[8] Chathuranga LS, Noordeen F, Abeykoon AMSB. Immune response to hepatitis B vaccine in a group of health care workers in SriLanka.Int J Infect Dis2013; 17:1078-9.
[9] Singh G, Singh MP,Walia I, Sarin C, Ratho RK.Screening for hepatitis B and C viral markers among nursing students in a tertiary care hospital. Indian J Med Microbiol2010; 28:78-9.
[10] Njemanze C, Erhabor O. Hepatitis B immunity status of healthcare workers in Lagos, Nigeria. Int J Biol Chem Sci2009; 3(6):1509-14.
[11] Ganczak M. A cross-sectional study in anti hepatitis B immune status in vaccinated healthcare workers in the west Pomeranian region of Poland. Hepat Mon2012; 12(3):185-9.
[12] Hedge S, Praveen BN, Pal S, Shetty SR, Ajila V, Babu S, Harini K. Serum antibody analysis following Hepatits B vaccination for occupational risk assessment among dental students.Nitte Univ J Health Sci2014;4(1):52-6.
[13] Puro V, de Carli G, Cicalini S, Soldani F, PAslslev U, Begovac J,et al. European recommendations for the management of healthcare workers occupationally exposed to hepatitis B virus and hepatitis C virus. Euro Surveil2005; 10:260-4.
[14] Kubba Ak, Taylor P.Graneek B, Strobel S.Non-responders to hepatitis B vaccination:A review. Commun Dis Public Health 2003; 6:106-12.
[15] Noh KW, Poland GA, Murray JA. Hepatitis B vaccine non-response and celiac disease. Am J Gastroentrol2003; 98:2289-92.
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[17] Sukirti, Pati NT, Sethi A, Agrawal K, Agrawal K, Kumar GT, Kumar M, Kaanan AT, Sarin SK. Low levels of awareness, vaccine overage and the need for boosters among health care workers in tertiary care hospitals in India. J Gastroenterol Hepatol2008; 23(11):1710-5.
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Cite This Article
  • APA Style

    Vijaya Doddaiah, Katta Janakiram, Shakthi Ramamurthy, Megha Sharathchandru, Yashaswini M Krishnamurthy, et al. (2015). Serologic Hepatitis B Immunity in Vaccinated Health Care Workers. American Journal of Life Sciences, 3(3), 162-166. https://doi.org/10.11648/j.ajls.20150303.16

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    ACS Style

    Vijaya Doddaiah; Katta Janakiram; Shakthi Ramamurthy; Megha Sharathchandru; Yashaswini M Krishnamurthy, et al. Serologic Hepatitis B Immunity in Vaccinated Health Care Workers. Am. J. Life Sci. 2015, 3(3), 162-166. doi: 10.11648/j.ajls.20150303.16

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    AMA Style

    Vijaya Doddaiah, Katta Janakiram, Shakthi Ramamurthy, Megha Sharathchandru, Yashaswini M Krishnamurthy, et al. Serologic Hepatitis B Immunity in Vaccinated Health Care Workers. Am J Life Sci. 2015;3(3):162-166. doi: 10.11648/j.ajls.20150303.16

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  • @article{10.11648/j.ajls.20150303.16,
      author = {Vijaya Doddaiah and Katta Janakiram and Shakthi Ramamurthy and Megha Sharathchandru and Yashaswini M Krishnamurthy and Santhya Seenivasen},
      title = {Serologic Hepatitis B Immunity in Vaccinated Health Care Workers},
      journal = {American Journal of Life Sciences},
      volume = {3},
      number = {3},
      pages = {162-166},
      doi = {10.11648/j.ajls.20150303.16},
      url = {https://doi.org/10.11648/j.ajls.20150303.16},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20150303.16},
      abstract = {The risk of acquiring hepatitis B infection through exposure for blood or its product is highest among health care workers. The most important approach for the prevention of occupational HBV infection is the use of hepatitis B vaccine among HCWs at risk. The present study was undertaken to assess the immune status of HBV vaccinated health care workers. A total of 268 HCWs of Adichunchanagiri Hospital and Research Centre attached to AIMS, B.G.Nagara were enrolled for the study .The study group includes doctors (113), medical & nursing students (61), nurses (59), technicians (15), group D workers (12) and others (8). The serum samples of the participants were tested for Anti-HBsAb levels using ELISA kit (Diasorin, Italy). Anti HBsAb titre of ≥ 10mIU/ml was considered as immune and < 10 mIU /ml as non-immune. The mean age of the study group was 29.49 years. Of the 268 participants 54.85% were female and 45.14% male. 23.5% had history of complete vaccination and 76.49% had incomplete vaccination (1/2 doses). 72.01% were immune and 27.98% non immune. There is a need for stringent and clear policies for HBV screening, vaccination and post vaccination assessment.},
     year = {2015}
    }
    

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  • TY  - JOUR
    T1  - Serologic Hepatitis B Immunity in Vaccinated Health Care Workers
    AU  - Vijaya Doddaiah
    AU  - Katta Janakiram
    AU  - Shakthi Ramamurthy
    AU  - Megha Sharathchandru
    AU  - Yashaswini M Krishnamurthy
    AU  - Santhya Seenivasen
    Y1  - 2015/05/12
    PY  - 2015
    N1  - https://doi.org/10.11648/j.ajls.20150303.16
    DO  - 10.11648/j.ajls.20150303.16
    T2  - American Journal of Life Sciences
    JF  - American Journal of Life Sciences
    JO  - American Journal of Life Sciences
    SP  - 162
    EP  - 166
    PB  - Science Publishing Group
    SN  - 2328-5737
    UR  - https://doi.org/10.11648/j.ajls.20150303.16
    AB  - The risk of acquiring hepatitis B infection through exposure for blood or its product is highest among health care workers. The most important approach for the prevention of occupational HBV infection is the use of hepatitis B vaccine among HCWs at risk. The present study was undertaken to assess the immune status of HBV vaccinated health care workers. A total of 268 HCWs of Adichunchanagiri Hospital and Research Centre attached to AIMS, B.G.Nagara were enrolled for the study .The study group includes doctors (113), medical & nursing students (61), nurses (59), technicians (15), group D workers (12) and others (8). The serum samples of the participants were tested for Anti-HBsAb levels using ELISA kit (Diasorin, Italy). Anti HBsAb titre of ≥ 10mIU/ml was considered as immune and < 10 mIU /ml as non-immune. The mean age of the study group was 29.49 years. Of the 268 participants 54.85% were female and 45.14% male. 23.5% had history of complete vaccination and 76.49% had incomplete vaccination (1/2 doses). 72.01% were immune and 27.98% non immune. There is a need for stringent and clear policies for HBV screening, vaccination and post vaccination assessment.
    VL  - 3
    IS  - 3
    ER  - 

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Author Information
  • Department of Microbiology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Karnataka, India

  • Department of Microbiology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Karnataka, India

  • Department of Microbiology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Karnataka, IndiaDepartment of Microbiology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Karnataka, India

  • Department of Microbiology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Karnataka, India

  • Department of Microbiology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Karnataka, India

  • Department of Microbiology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Karnataka, India

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